This PhD thesis is divided into three chapters: Introduction, Results and Discussion and Experimental Part. First part of chapter one is a review of compounds incorporating diamine moieties. Nowadays, it is one of the most investigated area of studies in several fields. Their uses in medicine and in chemistry will be discussed. However, attention will be refunded mainly on the use of diamines in organic synthesis as chiral auxiliaries, as chiral ligands in asymmetric synthesis or as organocatalysts. Additionally, the selected methods for their preparation will be given. In the second part of chapter one, the research area of the phosphorus-heteroatom heterocyclic compounds will be the main focus. This part of chapter one will present the cyclisation process of chiral diamines around the phosphorus atom. The cyclisation step affords heterocycles containing a trivalent or pentavalent stereogenic phosphorus atom. Finally, the application of these compounds in catalyzed transition metal transformations will be discussed. The investigation, presented in terms of the current thesis in chapter two, covers the preparation of various diamine ligands based on camphoric acid. The chiral diamine ligands with nitrogen atoms containing the same or different substituents will be described and their application in to the nitroaldol reaction presented which provides an easy access to chiral -nitroalcohols in high enantioselectivity up to 84% and excellent yield in up to 93%. The further transformations of the secondary chiral diamines into heterocycles containing phosphorus atom in quantitative yields in up to 97% without any purification and their application as ligands or as versatile chiral shift reagents will be also discussed in the second chapter. Lastly, the third chapter is the collection of experimental procedures and data of the presented work.