The effect of the choice of adhesives onto the properties of fiber-metal laminates (FMLs) was examined around the core idea of introducing a gradient of properties into the adhesive. Such a gradient can be helpful in reducing intrinsic stresses and stress concentrations under load. This concept was derived from nature, where it is ubiquitous at the interphases of dissimilar materials. Three fields of adhesives where examined: Rigid thermosetting epoxies, elastomeric thermosetting adhesives and thermoplastic adhesives based on polyolefins. The works approach is highly explorational, giving an overview of effects of the different adhesive classes of FMLs and also looks into innovative adhesive developments. It explores new concepts of modifying properties of existing adhesive types, the formulation of a water based elastomeric adhesive that incorporates nano particles, the testing of a new type of EPDM-based thermosetting adhesive and the use of thermoplastic adhesives for structural car body applications. The findings of the work are diverse, as the implementation of a material gradient in the adhesive is not superior to other tested modifications. An influence of an elasticity gradient was not evident in all tested systems, but very pronounced in others, especially those including elastomeric adhesives. The application of elastomeric adhesives bears a high potential for the introduction of special properties into the FML. In a combination of an elastomeric PU-based adhesive with a rigid epoxy-based adhesive, the order of the adhesives had a massive influence and the combination itself gave a significant advantage. A large part of this work deals with the development of an adhesive film that uses waterborne polyurethane dispersions as the binder.