Dietary sugar intake: International time trends in intake levels among children and adolescents and aspects of its relevance for subclinical inflammation [...] / by Karen Aimee Della Corte ; 1. Gutachterin: Prof. Dr. Anette E. Buyken, Paderborn University; 2. Gutachterin: Prof. Dr. Sarah Egert, University of Hohenheim. Paderborn, 2021
Content
- ACKNOWLEDGEMENTS
- PUBLICATIONS
- ZUSAMMENFASSUNG
- Table of Contents
- LIST OF FIGURES
- LIST OF TABLES
- ABBREVIATIONS
- 1 INTRODUCTION
- 2 THEORETICAL BACKGROUND
- 2.1 Dietary sugar among children and adolescents – Intake trends/levels and implications for health
- 2.1.1 Definitions of sugar and assessment methods
- 2.1.2 Recommended levels and trends of sugar intake
- 2.1.3 Children and adolescent populations
- 2.1.4 Obesity and chronic disease risk in children and adolescents
- 2.1.5 Longitudinal and repeat cross-sectional study designs
- 2.2 The influence of dietary sugar intake on systemic inflammation
- 2.2.1 Definition, development and prevalence of systemic inflammation
- 2.2.3 Possible pathophysiological mechanisms
- 2.2.4 Evidence from interventional and observational studies
- 2.3 The influence of dietary sugar intake on type 2 diabetes
- 3 AIMS AND RESEARCH QUESTIONS
- 4 GENERAL METHODOLOGY
- 4.1 Systematic literature review and meta-analysis
- 4.1.1 Methods and definition of systematic search and meta-analysis
- 4.1.2 Search strategy and terms
- 4.1.3 Study selection process and inclusion/exclusion criteria
- 4.1.4 Statistical methods of meta-analysis
- 4.2 Population and design of the DONALD Study (Study III)
- 4.3 Analytical study populations
- 4.4 24-hour urine samples
- 4.5 Dietary assessment
- 4.6 Anthropometric measurements
- 4.7 Medical examination, interview and parental data
- 4.8 Collection of blood parameters
- 4.9 Statistical considerations (Study III)
- 5 STUDIES
- 5.1 Study I - World Trends in Sugar-Sweetened Beverage and Dietary Sugar Intakes in Children and Adolescents: A Systematic Review
- 5.2 Study II - Effect of dietary sugar intake on biomarkers of subclinical inflammation: A systematic review and meta-analysis
- 5.3 Study III - The prospective association of dietary sugar intake in adolescence with type 2 diabetes and inflammatory markers in young adulthood
- 6. General Discussion
- 6.1 Additional considerations
- 6.1.1 Additional considerations (Study I)
- 6.1.2 Additional considerations (Study II)
- 6.1.3 Additional considerations (Study III)
- 6.2 Research Aims
- 6.2.1 Aim 1: World trends in SSB and dietary sugar
- 6.2.2 Aim 2: Dietary sugar and inflammation
- 6.2.3 Aim 3: Dietary sugar and T2D/inflammation
- 6.3 Public health relevance and practical implications
- 7. Conclusions and perspectives
- 8. References
- 9. Appendix
- 10. Versicherung